Ongoing Projects

National Program on Key Basic Research Project (973 Program) (NO. 2013CB734000)
Study on the compatibility of the synthetic microbial systems
合成微生物体系的适配性研究

Project of National Great New Drug Research and Development (NO. 2011ZX09102-011-11)
Preclinical study of the synergistic antifungal compound beauvericin
互动抗真菌药物白僵菌素的临床前研究

National Science and Technology Key Project on “Major Infectious Diseases such as HIV/AIDS, Viral Hepatitis Prevention and Treatment” (NO. 2013ZX10005004-005)
Synergistic anti-TB substances from TCMs and their medicinal mechanism
基于互动筛选技术揭示治疗耐药结核中药复方的物质基础及其作用机制

National Natural Science Foundation of China (Key Program) (NO.31430002)
Bioprospecting and genome mining of anti-TB bioactive molecules from marine verrucosispora Sp.
从海洋疣孢菌属中勘探和挖掘抗结核分枝杆菌活性的小分子

International Cooperation and Exchange of the National Natural Science Foundation of China (NSFC) (NO. 31320103911)
Targeting host-pathogen interactions for novel Antibiotics
针对病原菌与宿主互作关系筛选获得克服耐药菌的新型抗生素

National Science Fund for Distinguished Young Scholars (No. 31125002)
Study on mechanisms of antifungal drug resistance of natural products from Microbe
微生物活性物质抗耐药真菌的机制研究

China Ocean Mineral Resources R & D Association (NO. DY125-15-T-07)
Screening and Potential Valuation of Marine Microbes for Agriculture Application
深海农用活性微生物的筛选与应用潜力评价

Collaborative project “PharmaSea”
“Increasing Value and Flow in the Marine Biodiscovery Pipeline” (Grant agreement number312184)
欧盟第七框架计划

National Program on Key Basic Research Project (973 Program) (NO. 2012CB725203)
Characterization of artificial strain producing PHA
生物基材料工程菌株的功能检测与分析

National Program on Key Basic Research Project (973 Program) (NO. 2012CB721006)
Global transcriptional regulatory mechanism of Avermectin biosynthesis
阿维菌素生物合成基因相关全局转录调控模块作用机制解析

General Program of the National Natural Science Foundation of China (NSFC) (NO. 31170095)
The analysis and optimalization of the genes related to avemectin high-production
阿维菌素高产相关基因的解析与优化

National Natural Science Foundation of China (NSFC) (NO. 31400090)
Mechanism study of novel antimicrobials stimulating host immunity
新型宿主免疫调节抗菌化合物的作用机制研究

National Natural Science Foundation of China (NSFC) (NO. 81302678)
NanoDESI-LTQ-FT mass spectrum assisted MS/MS networking guided identification of anti-TB microbial natural products
基于NanoDESI-LTQ-FT质谱和小分子化合物网络快速鉴定微生物来源的抗结核活性成分

Cooperation program with enterprises
Construction of Coenzyme Q10 high-production strain
辅酶Q10菌种生产能力提高

Cooperation program with enterprises
Microbialtransformation of bioactive compounds from plant
植物活性物的微生物转化


Selected Publications

Projects & Grants